abstract：UNLABELLED:Dilated cardiomyopathy (DCM) is a severe heart disease characterized by progressive ventricular dilation and impaired systolic function of the left ventricle. We recently identified a novel pathogenic mutation in the LMNA gene in a family affected by DCM showing sudden death background. We now aimed to ident...

journal_title：Journal of proteomics

authors： Izquierdo I,Rosa I,Bravo SB,Guitián E,Pérez-Serra A,Campuzano O,Brugada R,Mangas A,García Á,Toro R

更新日期：2016-10-04 00:00:00

abstract：UNLABELLED:Leaf senescence is the last stage of leaf development that re-mobilizes nutrients from the source to sink. Here, we have utilized the soybean as a model system to unravel senescence-associated proteins (SAPs). A comparative proteomics approach was used at two contrasting stages of leaf development, namely ma...

journal_title：Journal of proteomics

authors： Gupta R,Lee SJ,Min CW,Kim SW,Park KH,Bae DW,Lee BW,Agrawal GK,Rakwal R,Kim ST

更新日期：2016-10-04 00:00:00

abstract：UNLABELLED:In the marine environment, bacteria from estuarine and coastal sediments are among the first targets of nanoparticle pollution; it is therefore relevant to improve the knowledge of interactions between bacteria and nanoparticles. In this work, the response of the marine bacterium Pseudomonas fluorescens BA3S...

journal_title：Journal of proteomics

authors： Poirier I,Kuhn L,Demortière A,Mirvaux B,Hammann P,Chicher J,Caplat C,Pallud M,Bertrand M

更新日期：2016-10-04 00:00:00

abstract：:Aspergillus fumigatus reproduces and infects host by forming a high number of small asexual spores (conidia). The velvet proteins are global transcriptional regulators governing the complex process of conidiogenesis in this fungus. Here, to further understand the velvet-mediated regulation, we carried out comparative ...

journal_title：Journal of proteomics

authors： Shin KS,Park HS,Kim Y,Heo IB,Kim YH,Yu JH

更新日期：2016-10-04 00:00:00

abstract：:Searching for potential predictors of meat color is a challenging task for the meat industry. In this study, the relationship between meat color parameters and the sarcoplasmic proteome of M. longissimuss lumborum (LL) and M. psoas major (PM) from Chinese Luxi yellow cattle during post-mortem storage (0, 5, 10 and 15d...

journal_title：Journal of proteomics

authors： Wu W,Yu QQ,Fu Y,Tian XJ,Jia F,Li XM,Dai RT

更新日期：2016-09-16 00:00:00

abstract：UNLABELLED:Seed storage albumins are abundant, water-soluble proteins that are degraded to provide critical nutrients for the germinating seedling. It has been established that the sunflower albumins encoded by SEED STORAGE ALBUMIN 2 (SESA2), SESA20 and SESA3 are the major components of the albumin-rich fraction of the...

journal_title：Journal of proteomics

authors： Franke B,Colgrave ML,Mylne JS,Rosengren KJ

更新日期：2016-09-16 00:00:00

abstract：UNLABELLED:A literature survey covering the presence of bioactive peptides in plant-derived foodstuffs is presented. Examples are given of plant peptides associated with a beneficial effect on human health. The main bioactive effects of these peptides are defined and their mechanism of action described, when known. Cur...

journal_title：Journal of proteomics

authors： Maestri E,Marmiroli M,Marmiroli N

更新日期：2016-09-16 00:00:00

abstract：UNLABELLED:Quantification of the antigens hemagglutinin and neuraminidase in influenza vaccines has been reported using an antibody-free liquid chromatography-mass spectrometry (LC-MS) based method known as MS(E) "Hi3". This approach is based on the average signal intensity of the three most intense tryptic peptides re...

journal_title：Journal of proteomics

authors： Smith DG,Gingras G,Aubin Y,Cyr TD

更新日期：2016-09-02 00:00:00

abstract：UNLABELLED:Phyllomedusine frogs are an extraordinary source of biologically active peptides. At least 8 families of antimicrobial peptides have been reported in this frog clade, the dermaseptins being the most diverse. By a peptidomic approach, integrating molecular cloning, Edman degradation sequencing and tandem mass...

journal_title：Journal of proteomics

authors： Proaño-Bolaños C,Zhou M,Wang L,Coloma LA,Chen T,Shaw C

更新日期：2016-09-02 00:00:00

abstract：UNLABELLED:The vacuole is by far the largest multifunctional organelle in fruits and plays a functional role in fruit development and fruit quality. Despite its significance, little information exists pertaining to the role of the vacuolar membrane (tonoplast) in the process of fruit senescence. In the present study, a...

journal_title：Journal of proteomics

authors： Liu R,Wang Y,Qin G,Tian S

更新日期：2016-09-02 00:00:00

abstract：UNLABELLED:Escherichia coli is a commensal microorganism of the gastrointestinal tract of animals and humans and it is an excellent model organism for the study of antibiotic resistance mechanisms. The resistance transmission and other characteristics of bacteria are based on different types of gene transfer occurring ...

journal_title：Journal of proteomics

authors： Magalhães P,Pinto L,Gonçalves A,Araújo JE,Santos HM,Capelo JL,Saénz Y,de Toro M,Torres C,Chambon C,Hébraud M,Poeta P,Igrejas G

更新日期：2016-08-11 00:00:00

abstract：UNLABELLED:The reproductive stage of Paracentrotus lividus strongly influences product quality that, in turn, impacts significantly on the market price. Large, compact and sweet gonads are preferred, and sensory attributes are positively related to the ratio of nutritive phagocytes to gametes. Gonads at advanced matura...

journal_title：Journal of proteomics

authors： Ghisaura S,Loi B,Biosa G,Baroli M,Pagnozzi D,Roggio T,Uzzau S,Anedda R,Addis MF

更新日期：2016-07-20 00:00:00

abstract：UNLABELLED:Plant roots, the hidden half of plants, play a vital role in manganese (Mn) toxicity tolerance. However, molecular mechanisms underlying root adaptation to Mn toxicity remain largely unknown. In this study, soybean (Glycine max) was used to investigate alterations of root morphology and protein profiles in r...

journal_title：Journal of proteomics

authors： Chen Z,Yan W,Sun L,Tian J,Liao H

更新日期：2016-06-30 00:00:00

abstract：UNLABELLED:The long cultivation of field pea led to an enormous diversity which, however, seems to hold just little resistance against the ascochyta blight disease complex. The potential of below ground microbial symbiosis to prime the immune system of Pisum for an upcoming pathogen attack has hitherto received little ...

journal_title：Journal of proteomics

authors： Desalegn G,Turetschek R,Kaul HP,Wienkoop S

更新日期：2016-06-30 00:00:00

abstract：UNLABELLED:Water stress (WS) predisposes peanut plants to fungal infection resulting in pre-harvest aflatoxin contamination. Major changes during water stress including oxidative stress, lead to destruction of photosynthetic apparatus and other macromolecules within cells. Two peanut cultivars with diverse drought tole...

journal_title：Journal of proteomics

authors： Katam R,Sakata K,Suravajhala P,Pechan T,Kambiranda DM,Naik KS,Guo B,Basha SM

更新日期：2016-06-30 00:00:00

abstract：UNLABELLED:About 75% of plant yield potential has been estimated to be lost to environmental stresses, even in developed agricultures. To facilitate the biotechnological improvement of crop productivity, genes and proteins that control crop adaptation to a wide range of environments will need to be identified. Due to t...

journal_title：Journal of proteomics

authors： Mousavi SA,Pouya FM,Ghaffari MR,Mirzaei M,Ghaffari A,Alikhani M,Ghareyazie M,Komatsu S,Haynes PA,Salekdeh GH

更新日期：2016-06-30 00:00:00

abstract：UNLABELLED:The importance of UV stress and its side-effects over the loss of plant productivity in forest species demands a deeper understanding of how pine trees respond to UV irradiation. Although the response to UV stress has been characterized at system and cellular levels, the dynamics within the nuclear proteome ...

journal_title：Journal of proteomics

authors： Pascual J,Alegre S,Nagler M,Escandón M,Annacondia ML,Weckwerth W,Valledor L,Cañal MJ

更新日期：2016-06-30 00:00:00

abstract：UNLABELLED:Male infertility of cattleyak due to spermatogenic arrest greatly restricts their effective utilization in yak breeding. Although much work has been done to investigate the mechanisms of spermatogenic arrest, there is no information regarding the differences of protein composition between cattleyak and yak t...

journal_title：Journal of proteomics

authors： Yu S,Cai X,Sun L,Zuo Z,Mipam T,Cao S,Shen L,Ren Z,Chen X,Yang F,Deng J,Ma X,Wang Y

更新日期：2016-06-16 00:00:00

abstract：UNLABELLED:Although several new biomarkers have been recently proposed for psoriasis (Ps) and psoriasis arthritis (PsA), nothing is known about their diagnostic sensitivity and specificity, and their routine use. We therefore searched in-depth for new biomarker candidates using a biobank with EDTA-plasma from 158 indiv...

journal_title：Journal of proteomics

authors： Reindl J,Pesek J,Krüger T,Wendler S,Nemitz S,Muckova P,Büchler R,Opitz S,Krieg N,Norgauer J,Rhode H

更新日期：2016-05-17 00:00:00

abstract：UNLABELLED:Erwinia amylovora is a Gram-negative plant pathogen that causes fire blight. This disease affects most members of the Rosaceae family including apple and pear. Here, an infection model is introduced to study proteomic changes in a highly virulent E. amylovora strain upon interaction with its host as compared...

journal_title：Journal of proteomics

authors： Holtappels M,Vrancken K,Noben JP,Remans T,Schoofs H,Deckers T,Valcke R

更新日期：2016-04-29 00:00:00

abstract：UNLABELLED:Marine bioadhesives have unmatched performances in wet environments, being an inspiration for biomedical applications. In sea urchins specialized adhesive organs, tube feet, mediate reversible adhesion, being composed by a disc, producing adhesive and de-adhesive secretions, and a motile stem. After tube foo...

journal_title：Journal of proteomics

authors： Lebesgue N,da Costa G,Ribeiro RM,Ribeiro-Silva C,Martins GG,Matranga V,Scholten A,Cordeiro C,Heck AJ,Santos R

更新日期：2016-04-14 00:00:00

abstract：UNLABELLED:To further elucidate the molecular mechanism of cytoplasmic male sterility (CMS) in soybean, a differential proteomic analysis was completed between the CMS line NJCMS1A and its maintainer NJCMS1B using iTRAQ-based strategy. As a result, 180 differential abundance proteins (DAPs) were identified, of which, 6...

journal_title：Journal of proteomics

authors： Li J,Ding X,Han S,He T,Zhang H,Yang L,Yang S,Gai J

更新日期：2016-04-14 00:00:00

abstract：UNLABELLED:Plant pathogens face different environmental clues depending on the stage of the infection cycle they are in. Fusarium graminearum infects small grain cereals producing trichothecenes type B (TB) that act as virulence factor in the interaction with the plant and have important food safety implications. This ...

journal_title：Journal of proteomics

authors： Pasquali M,Serchi T,Cocco E,Leclercq CC,Planchon S,Guignard C,Renaut J,Hoffmann L

更新日期：2016-03-30 00:00:00

abstract：:Parasitic diseases have a great impact in human and animal health. The gold standard for the diagnosis of the majority of parasitic infections is still conventional microscopy, which presents important limitations in terms of sensitivity and specificity and commonly requires highly trained technicians. More accurate m...

journal_title：Journal of proteomics

authors： Sánchez-Ovejero C,Benito-Lopez F,Díez P,Casulli A,Siles-Lucas M,Fuentes M,Manzano-Román R

更新日期：2016-03-16 00:00:00

abstract：UNLABELLED:The sea cucumber Apostichopus japonicus is becoming an excellent model marine invertebrate for studies of environmentally-induced aestivation. Reversible protein phosphorylation as a regulatory mechanism in aestivation is known for some terrestrial aestivators but has never before been documented in sea cucu...

journal_title：Journal of proteomics

authors： Chen M,Zhu A,Storey KB

更新日期：2016-03-01 00:00:00

abstract：UNLABELLED:Increasing atmospheric carbon dioxide results in ocean acidification and warming, significantly impacting marine invertebrate larvae development. We investigated how ocean acidification in combination with warming affected D-veliger larvae of the Pacific oyster Crassostrea gigas. Larvae were reared for 40h u...

journal_title：Journal of proteomics

authors： Harney E,Artigaud S,Le Souchu P,Miner P,Corporeau C,Essid H,Pichereau V,Nunes FLD

更新日期：2016-03-01 00:00:00

abstract：:Flightin is a myosin binding phosphoprotein that originated in the ancestor to Pancrustacea ~500 MYA. In Drosophila melanogaster, flightin is essential for length determination and flexural rigidity of thick filaments. Here, we show that among 12 Drosophila species, the N-terminal region is characterized by low sequen...

journal_title：Journal of proteomics

authors： Lemas D,Lekkas P,Ballif BA,Vigoreaux JO

更新日期：2016-03-01 00:00:00

abstract：UNLABELLED:The microbiological safety of milk is typically guaranteed by thermal treatments, such as pasteurization and ultra high temperature (UHT) treatment, whereas infant formula (IF) is often produced at even harsher conditions including a drying process. Thermal treatments have raised concerns, as they may denatu...

journal_title：Journal of proteomics

authors： Milkovska-Stamenova S,Hoffmann R

更新日期：2016-02-16 00:00:00

abstract：UNLABELLED:Glycosylation is the most complex post-translational modification. Thus, it contributes to versatile chemical compositions of proteins, leading to high amounts of protein species. The structural heterogeneity of glycoproteins was also described by the definition of glycoforms. We therefore introduced a new t...

journal_title：Journal of proteomics

authors： Rosenlöcher J,Sandig G,Kannicht C,Blanchard V,Reinke SO,Hinderlich S

更新日期：2016-02-16 00:00:00

abstract：UNLABELLED:RNA interference offers effective control of several economically important insect pests. Bemisia tabaci is an important field crop pest, which causes significant yield loss worldwide. In our earlier study, we have demonstrated successful control of B. tabaci through transgenic plant mediated RNAi. However, ...

journal_title：Journal of proteomics

authors： Mishra M,Saurabh S,Maurya R,Mudawal A,Parmar D,Singh PK

更新日期：2016-01-30 00:00:00

abstract：UNLABELLED:Pluripotent stem cell-derived committed neural precursors are an important source of cells to treat neurodegenerative diseases including spinal cord injury. There remains an urgency to identify markers for monitoring of neural progenitor specificity, estimation of neural fate and follow-up correlation with t...

journal_title：Journal of proteomics

authors： Tyleckova J,Valekova I,Zizkova M,Rakocyova M,Marsala S,Marsala M,Gadher SJ,Kovarova H

更新日期：2016-01-30 00:00:00

abstract：UNLABELLED:The venom proteome of the Malayan blue coral snake, Calliophis bivirgata flaviceps from west Malaysia was investigated by 1D-SDS-PAGE and shotgun-LCMS/MS. A total of 23 proteins belonging to 11 protein families were detected from the venom proteome. For the toxin proteins, the venom consists mainly of phosph...

journal_title：Journal of proteomics

authors： Tan CH,Fung SY,Yap MK,Leong PK,Liew JL,Tan NH

更新日期：2016-01-30 00:00:00

abstract：:Functional regulation of NMDA receptor (NMDAR) by the activation of α7 nicotinic acetylcholine receptor (α7nAChR) has been reported, although the molecular signaling pathway underlying this process remains largely unknown. We employed a label-free quantitative proteomics approach to identify potential intracellular mo...

journal_title：Journal of proteomics

authors： Zhang H,Li T,Li S,Liu F

更新日期：2016-01-10 00:00:00

abstract：:Snake venoms are composed of approximately 90% of proteins with several pharmacological activities having high potential in research as biological tools. One of the most abundant compounds is phospholipases A2 (PLA2), which are the most studied venom protein due to their wide pharmacological activity. Using a combinat...

journal_title：Journal of proteomics

authors： Carregari VC,Dai J,Verano-Braga T,Rocha T,Ponce-Soto LA,Marangoni S,Roepstorff P

更新日期：2016-01-10 00:00:00

abstract：UNLABELLED:Milk is a highly nutritious natural product that provides not only a rich source of amino acids to the consumer but also hundreds of bioactive peptides and proteins known to elicit health-benefitting activities. We investigated the milk protein profile produced by Holstein and Jersey dairy cows maintained un...

journal_title：Journal of proteomics

authors： Tacoma R,Fields J,Ebenstein DB,Lam YW,Greenwood SL

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:Somatic embryogenesis, an important biotechnological technique, has great potential for application in sugarcane breeding and micropropagation. Polyamines have been associated with the regulation of several physiological processes, including the acquisition of embryogenic competence and somatic embryogenesis...

journal_title：Journal of proteomics

authors： Reis RS,Vale Ede M,Heringer AS,Santa-Catarina C,Silveira V

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:Label-free LC-MS/MS proteomics has proven itself to be a powerful method for evaluating protein identification and quantification from complex samples. For comparative proteomics, several methods have been used to detect the differential expression of proteins from such data. We have assessed seven methods u...

journal_title：Journal of proteomics

authors： Langley SR,Mayr M

更新日期：2015-11-03 00:00:00

abstract：:Selecting the most appropriate surrogate peptides to represent a target protein is a major component of experimental design in Multiple Reaction Monitoring (MRM). Our software PeptidePicker with its v-score remains distinctive in its approach of integrating information about the proteins, their tryptic peptides, and t...

journal_title：Journal of proteomics

authors： Mohammed Y,Borchers CH

更新日期：2015-11-03 00:00:00

abstract：:The reprogrammed lipopolysaccharide (LPS) pathway has been reported to render patients more susceptible to the development of post-traumatic multiple organ dysfunction syndrome (MODS). To facilitate thorough understanding of this mechanism, a phosphoproteomic study was utilized to screen the potential signaling molecu...

journal_title：Journal of proteomics

authors： Xu E,Chen J,Wang Y,Ke Z,Luo S,Zou Z

更新日期：2015-10-14 00:00:00

abstract：UNLABELLED:Next generation sequencing and proteomics have helped to comprehensively characterize gene expression in tick salivary glands at both the transcriptome and the proteome level. Functional data are, however, lacking. Given that tick salivary secretions are critical to the success of the tick transmission lifec...

journal_title：Journal of proteomics

authors： Kotál J,Langhansová H,Lieskovská J,Andersen JF,Francischetti IM,Chavakis T,Kopecký J,Pedra JH,Kotsyfakis M,Chmelař J

更新日期：2015-10-14 00:00:00